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| Nagase Medicals Co., Ltd. | Teikoku Chemical Industries Co., Ltd. |
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| 1938 | Company established. Factory completed in Itami City, Hyogo Prefecture. | |
| 1941 | Started to sell Percamin, a local anesthetic (the first Japanese-made local anesthetic). |
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| 1972 | The Pharmaceutical Products Division of Nagase & Co., Ltd. was dissolved so as to form a new sales company for ethical drugs of Teikoku Chemical Industries Co., Ltd. The new company capitalized at 3 million yen. |
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| 1972 | Capital increased to 48 million yen. | |
| 1979 | Completed work to comply with GMP. | |
| 1984 | Started to manufacture and sell health food products. | |
| 1987 | Started to sell Lonmiel Capsule®, a new anti-ulcer agent. |
Completed the development of a new anti-ulcer agent, Lonmiel Capsule®, and started to sell it. |
| 1993 | Established Nagase Alphametics Co., Ltd., a cosmetics and health food products manufacturing company, under a joint capital investment with Nagase & Co., Ltd. | |
| 1997 | Pharmaceuticals building completed in the Itami Plant. | |
| 2001 March |
Business of the Pharmaceuticals Business Division was transferred from Teikoku Chemical Industries Co., Ltd. to Nagase Medicals Co., Ltd., which was then reorganized to be a pharmaceuticals manufacturing company with its capital increased to 498 million yen. | |
| 2001 October |
Business of the Sales Division for ethical drugs was transferred to Merck Hoei Ltd. (currently Merck Pharmaceutical Co.), and Nagase Medicals was reorganized to be a pharmaceuticals development and manufacturing company. | |
| 2003 January |
Injection manufacturing building dedicated to injections requiring control (e.g. highly active drugs) was completed. | |
| 2004 June |
Laboratory building completed. | |
