HOME >> Manufacturing system for liquid preparations
Bottle filling lines (for oral and external liquid preparations) were newly established in 2004 and filling operations are performed within a laminar flow booth. A wide range of formulations from ordinary types of syrups through to liquid preparations with high viscosity, liquid dosage forms with weak antiseptic power are manufactured.
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| Process | Name of facility or equipment | Manufacturer & model | Capacity & specifications |
| Liquids line (1) | Solution preparation tank | Nishida Doukousho Co., Ltd. | 500 L with jacket: 85ºC |
| Rotary bottle washer | Oogi Machinery Co., Ltd. SR-24 | Capable of handling 100 mL vials, 20 vials/min | |
| Filling machine | Oogi Machinery Co., Ltd. | Capable of handling 100 mL vials | |
| Seamer | Yoshimura Tekkosho E-3B-OCCM | ||
| Visual inspection Machine | Oogi Machinery Co., Ltd. | ||
| Liquids line (2) | Solution tank | Daiei Inc. | 100 L (Teflon coated) |
| Preparation tank | Daiei Inc. | 2000 L with jacket: 85ºC | |
| Storage tank | Daiei Inc. | 2000 L | |
| Bottle washer | Nagata seisakusho Co., Ltd. NBR-6 | Capable of handling 100 mL and 500 mL bottles, 40 bottles/min., WFI washing, air washing |
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| Filling machine | KT. MFG. Co., Ltd. 5FL-WT | Capable of handling 100 and 500 mL bottles, 40 bottles/min., weight-filling method | |
| Capper | KT. MFG. Co., Ltd. 2C-TC | Capable of handling 100 and 500 mL bottles, 40 bottles/min., torque-controlled method | |
| Labeling and packaging | Bottle labeler | Sun-Tec Company,Ltd. ST-VRHP | up to 1800 bottles/h |
| Cartoning machine | Fuji Astec Co., Ltd. CMVA | up to 1800 bottles/h |
| Process | Name of facility or equipment | Manufacturer & model | Capacity & specifications |
| Preparation of solution | Solution tank | Trytech Co.,Ltd. | 100 L |
| HCl storage tank | Trytech Co.,Ltd. | 100 L | |
| Preparation tank | Trytech Co.,Ltd. | 2000 L | |
| Heat sterilizer for liquid | Okawara Corporation. KLP-5 | 350 L/h maximum | |
| Storage tank | Trytech Co.,Ltd. | 2000 L | |
| Filling | Tube feeder | IWK Verpackungstechnik GmbH TZ102 | 160 tubes/min. |
| Tube filling and Seal printer | IWK Verpackungstechnik GmbH TFS-80-2 | Hopper capacity: 55 L, 160 tubes/min. | |
| Tube inside inspection machine | Pharmalead Engineering Co., Ltd. | 180 tubes/min. | |
| Weight checker | Anritsu Corporation KW6003FP2C | Maximum capacity: 60 g, Sensitivity: 0.05 g | |
| Tube puncture & Seal inspection machine | Pharmalead Engineering Co., Ltd. | 170 tubes/min. | |
| Packaging | Cartoner (individual packaging) | O-M, Ltd. | 200 tubes/min. |
| Caser | O-M, Ltd. | 2 cases/min. |
